Biochemical Pharmacology
Theory: 3 hours/week | Tutorials: 2 hours/week | ECTS Units: 5
Content – Aim of the course
Pharmacology requires by definition the coexistence of chemistry, anatomy, physiology, molecular biology and pathology for comprehending why, when and how the drugs can be used in the treatment of illnesses. In this course are presented the modes of drug action at the molecular level. In the first part the general modes of action of drugs are analyzed and in the second, the pharmaceutical treatment of various illnesses will be reviewed. It is a course that it has as objective relays the gap between the molecular mechanisms of drugs and their therapeutic use.
Analytical Description of the Course
General Principles of Pharmacology
- Introduction (What is Pharmacology, History, Development of New Drugs)
- Drug nomenclature and drug classification system
- General principles of drug action
- Quantitative expression of drug action
- Pharmacogenomics- factors that influence drug action
Pharmaceutical treatment of illnesses
- Drugs that affect the nervous system
- Drugs that affect the cardiovascular system
- Drugs that affect the respiratory system
- Drugs that affect the urinary system
- Drugs that affect the digestive system
- Bacterial infections-antibiotics
- Chemotherapy-anticancer drugs
Tutorials
Each course chapter will be accompanied with tutorial classes during which students (in groups) are presenting (both in written and orally) recent articles (reviews) regarding molecular pharmacology topics.
Assessment
Students will be graded based on written exams at the end of the semester (80%) and based on the tutorial grades (20%). The grade of the tutorials is based on the written and oral presentation of the review articles.
Reading Suggestions
- Goodman & Gilman’s The Pharmacological Basis of Therapeutics, J.Hardman (editor), L. Limbird (editor) and A. Gilman (editor), 10th edition, MacGraw-Hill, 2001.
- Pharmacology, Page C.P., Curtis, M.J. Sutter, M.C. et al, Medical Edition Paschalidi, 2000.
- Pharmacology, Harvey, R.A. and Champe P.C. Edition Parisianou, 1995.
- Color Atlas of Pharmacology, Thieme Medical Publishers, Authors: Luellmann, Mohr, Hein, Bieger. 3rd edition, 2005
Teaching Material / E-class
Lecturers
Kalliopi Liadaki (Course Coordinator)
